PE-22-28
PE-22-28 is an experimental neuroactive peptide with promising implications for mental health, cognitive enhancement, and neuroprotection. Its short, stable structure makes it valuable for research exploring the therapeutic potential of PACAP derivatives in modulating emotional and neurological function.
$65.00
This product remains in its original powdered state without being reconstituted.
PE-22-28 (Synthetic Peptide)
Neuropeptide Fragment for Mood, Stress, and Cognitive Research
Overview
PE-22-28 is a synthetic peptide fragment derived from the pituitary adenylate cyclase-activating polypeptide (PACAP). It represents amino acids 22–28 of the parent peptide and is being studied for its neuromodulatory and neuroprotective properties. Research suggests that PE-22-28 may help regulate stress responses, emotional balance, and cognitive performance through its interaction with PAC1 and VPAC receptors in the central nervous system.
Mechanism of Action
PE-22-28 exerts its effects by modulating cAMP signaling and influencing neurotransmitter release, particularly in pathways related to mood regulation and neuroplasticity. It has demonstrated potential to:
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Reduce anxiety-like behavior in preclinical models
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Enhance neuroprotection against oxidative and excitotoxic stress
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Support memory and learning through synaptic regulation
Key Research Areas
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Mood and anxiety regulation
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Neuroprotection and neuronal repair
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Cognitive and behavioral neuroscience
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Stress adaptation mechanisms
PRODUCTS ARE FOR RESEARCH PURPOSES ONLY
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